A "switching on" fluorescent chemodosimeter of selectivity to Zn2+ and its application to MCF-7 cells

Chem Commun (Camb). 2010 Oct 14;46(38):7169-71. doi: 10.1039/c0cc01687j. Epub 2010 Sep 1.

Abstract

A highly sensitive and selective 1,8-naphthyridine-based fluorescent chemodosimeter for Zn(2+) has been designed, synthesized, and applied to the detection of intracellular Zn(2+).

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques / methods*
  • Cell Line, Tumor
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Humans
  • Naphthyridines / chemical synthesis
  • Naphthyridines / chemistry*
  • Sensitivity and Specificity
  • Spectrometry, Fluorescence / methods
  • Zinc / analysis*

Substances

  • Fluorescent Dyes
  • Naphthyridines
  • Zinc