A 76-year-old woman was admitted to our institution because of high fever and erythema in the upper body with right back pain, and was given a diagnosis of Sweet's syndrome. She also had abdominal pain and developed hematochezia from the fourth hospitalization day. Double balloon enteroscopy detected multiple ulcers with a punched-out appearance at the terminal ileum. Endoscopic hemostasis of the ulcers was achieved using a hemoclip for treatment of a focal pulsating hemorrhage. After oral administration of prednisolone (PSL), both the ileal ulcer and erythema disappeared. The daily dosage of PSL was tapered. Since termination of PSL administration, there has been no recurrence of either Sweet's syndrome or ileal ulcer. We report a rare case of Sweet's syndrome complicated by bleeding ileal ulcers.