Stereochemistry and NMR data assignment of cyclopeptide alkaloids from Zizyphus oxyphylla

Nat Prod Commun. 2010 Aug;5(8):1205-8.

Abstract

The structures of (3S,7R,13S)-6-[2-(dimethylamino)-3-phenylpropanoyl]-19-methoxy-2-oxa-6,9,15-triazatetracyclo[16.3.1.0(3,7). 0(9,13)]docosa-1-(22),16,18,20-tetraene-8,14-dione (1), nummularin-C (2) and nummularin-R (3) have been previously determined mainly based on mass spectrometric data. Stereochemistry and complete 1H and 13C NMR spectroscopic data assignments of these compounds are now described. Compounds 1 and 2 are reported for the first time from Zizyphus oxyphylla.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry*
  • Magnetic Resonance Spectroscopy / methods*
  • Molecular Conformation
  • Peptides, Cyclic / chemistry*
  • Ziziphus / chemistry*

Substances

  • Alkaloids
  • Peptides, Cyclic