The need for quality improvement in sweat testing infants after newborn screening for cystic fibrosis

Vicky A Legrys; Susanna A McColley; Zhanhai Li; Philip M Farrell

doi:10.1016/j.jpeds.2010.07.053

The need for quality improvement in sweat testing infants after newborn screening for cystic fibrosis

J Pediatr. 2010 Dec;157(6):1035-7. doi: 10.1016/j.jpeds.2010.07.053. Epub 2010 Sep 16.

Authors

Vicky A Legrys¹, Susanna A McColley, Zhanhai Li, Philip M Farrell

Affiliation

¹ School of Medicine, Division of Clinical Laboratory Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Abstract

The proportion of insufficient sweat tests after positive newborn screening for cystic fibrosis was determined. Infants ≤ 3 months old had a mean (± standard deviation) rate of 7.2% (± 7.6) (range, 0% to 40%). Collection methods did not affect the rates. The high and variable rates indicate a need for quality improvement.

Publication types

Multicenter Study

MeSH terms

Cystic Fibrosis / diagnosis*
Humans
Infant, Newborn
Neonatal Screening / standards*
Prospective Studies
Quality of Health Care / standards*
Sweat* / chemistry

Grants and funding

R01 DK034108/DK/NIDDK NIH HHS/United States