Exploratory study of factors associated with adverse clinical features in patients presenting with non-fatal drug overdose/self-poisoning to the ambulance service

Emerg Med J. 2011 Oct;28(10):892-4. doi: 10.1136/emj.2009.086140. Epub 2010 Sep 15.

Abstract

Aim: To investigate the factors associated with adverse clinical features presented by drug overdose/self-poisoning patients and the treatments provided.

Methods: Historical patient records collected over 3 months from ambulance crews attending non-fatal overdoses/self-poisoning incidents were reviewed. Logistic regression was used to investigate predictors of adverse clinical features (reduced consciousness, obstructed airway, hypotension or bradycardia, hypoglycaemia) and treatment.

Results: Of 22,728 calls attended to over 3 months, 585 (rate 26/1000 calls) were classified as overdose or self-poisoning. In the 585 patients identified, paracetamol-containing drugs were most commonly involved (31.5%). At least one adverse clinical feature occurred in 103 (17.7%) patients, with higher odds in men and opiate overdose or illegal drugs. Older patients and patients with reduced consciousness were more likely to receive oxygen. The latter also had a greater chance of receiving saline.

Conclusion: Non-fatal overdose/self-poisoning accounted for 2.6% of patients attended by an ambulance. Gender, illegal drugs or opiates were important predictors of adverse clinical features. The treatments most often provided to patients were oxygen and saline.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Drug Overdose / epidemiology*
  • Drug Overdose / therapy
  • Emergency Medical Services / statistics & numerical data*
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Risk Factors
  • Suicide, Attempted / statistics & numerical data*
  • Young Adult