Self-assembled encapsulation systems with pH tunable release property based on reversible covalent bond

Chem Commun (Camb). 2010 Oct 28;46(40):7569-71. doi: 10.1039/c0cc02654a. Epub 2010 Sep 17.

Abstract

Dynamic diblock polymer PS-r-PEG formed via reversible acylhydrazone connection can be used to construct a pH-responsive self-assembled encapsulation system with high stability and sustained-release property, which shows potential in drug delivery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Delayed-Action Preparations / chemical synthesis
  • Delayed-Action Preparations / chemistry*
  • Hydrogen-Ion Concentration
  • Magnetic Resonance Spectroscopy
  • Microscopy, Electron, Transmission
  • Molecular Structure
  • Polyethylene Glycols / chemical synthesis
  • Polyethylene Glycols / chemistry*
  • Polystyrenes / chemical synthesis
  • Polystyrenes / chemistry*
  • Porphyrins / administration & dosage

Substances

  • Delayed-Action Preparations
  • Polystyrenes
  • Porphyrins
  • polyethylene glycol-polystyrene
  • Polyethylene Glycols