Human skin allografts as a useful adjunct in the treatment of purpura fulminans

J Wound Care. 2010 Aug;19(8):355-8. doi: 10.12968/jowc.2010.19.8.77714.

Abstract

Objective: The aim of this report is to discuss the role of human skin allografts in surgical coverage procedures for patients with purpura fulminans.

Method: We describe cases of purpura fulminans in three adults and one infant treated at our burns unit between October 2006 and January 2008.

Results: The application of cryopreserved human skin allografts allowed us to obtain immediate wound closure after necrosis excision and enabled our team to subsequently perform autografts on favourable graft recipient sites.

Conclusion: Recourse to human skin allografts must be considered a pertinent therapeutic option in patients with purpura fulminans.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amputation, Surgical
  • Cryopreservation
  • Debridement
  • Fatal Outcome
  • Female
  • Humans
  • Infant
  • Male
  • Meningococcal Infections / microbiology
  • Necrosis
  • Neisseria meningitidis, Serogroup C
  • Patient Selection
  • Pneumococcal Infections / microbiology
  • Purpura Fulminans / microbiology
  • Purpura Fulminans / pathology
  • Purpura Fulminans / therapy*
  • Shock, Septic / microbiology
  • Skin Care
  • Skin Transplantation / methods*
  • Transplantation, Homologous / methods
  • Treatment Outcome
  • Wound Healing