Modulation of orbitofrontal response to amphetamine by a functional variant of DAT1 and in vitro confirmation

Mol Psychiatry. 2011 Feb;16(2):124-6. doi: 10.1038/mp.2009.6. Epub 2010 Sep 21.
No abstract available

Publication types

  • Letter
  • Randomized Controlled Trial

MeSH terms

  • Amphetamine / pharmacology*
  • Decision Making / drug effects*
  • Decision Making / physiology
  • Dopamine Plasma Membrane Transport Proteins / genetics*
  • Dopamine Uptake Inhibitors / pharmacology*
  • Games, Experimental
  • Genotype
  • Humans
  • Hyperkinesis / chemically induced
  • Hyperkinesis / genetics*
  • Image Processing, Computer-Assisted / methods
  • Magnetic Resonance Imaging
  • Minisatellite Repeats / genetics
  • Oxygen / blood
  • Prefrontal Cortex / blood supply
  • Prefrontal Cortex / drug effects*
  • Reward

Substances

  • Dopamine Plasma Membrane Transport Proteins
  • Dopamine Uptake Inhibitors
  • SLC6A3 protein, human
  • Amphetamine
  • Oxygen