Reperfusionable focal cerebral ischemia by embolization to the middle cerebral artery with nylon thread adhered to sponge was studied in rats. It was divided into 2 groups: permanent embolization and embolization for 3 hours. Neurological symptoms, degree of brain swelling and size of cerebral infarction of these animals were observed. The laboratory statistics was no difference between the two groups. But it was found in pathological specimens that infarction area were limited in the basal-ganglion with perivascular hemorrhage in 3 rats after reperfusion. Establishment of the model, symptoms of rats, results of laboratory and it's clinical significances were discussed.