Abstract
A 65-year-old woman with a history of gastric bleeding, breast cancer, antineoplastic chemotherapy, and prednisone use presented with a fever, chest pain, a dry cough, hypotension, and prominent pulmonary bronchovascular markings. She was treated with piperacillin-tazobactam and azithromycin and rapidly improved. Six days later, the blood culture grew a pleomorphic Gram-negative bacillus. Initial subculture failed, but the organism was identified as Helicobacter pylori by sequencing the 16S rRNA gene. The bacterium eventually grew on brucella agar upon extended incubation.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
MeSH terms
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Aged
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Antineoplastic Agents / adverse effects
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Antineoplastic Agents / therapeutic use
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Bacteremia / microbiology
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Bacteremia / pathology*
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Blood / microbiology
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Breast Neoplasms / drug therapy
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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DNA, Ribosomal / chemistry
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DNA, Ribosomal / genetics
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Drug-Related Side Effects and Adverse Reactions
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Female
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Helicobacter Infections / microbiology
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Helicobacter Infections / pathology*
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Helicobacter pylori / isolation & purification*
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Helicobacter pylori / pathogenicity
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Humans
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Immunocompromised Host
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Molecular Sequence Data
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RNA, Ribosomal, 16S / genetics
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Sequence Analysis, DNA
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Systemic Inflammatory Response Syndrome / microbiology
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Systemic Inflammatory Response Syndrome / pathology*
Substances
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Antineoplastic Agents
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DNA, Bacterial
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DNA, Ribosomal
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RNA, Ribosomal, 16S