Advances in radiology have led to improvements in care for patients with urinary tract stones. One of the most promising imaging techniques is dual-energy CT, which enables more accurate characterization of stone disease than other imaging techniques and helps direct therapy at the time of the initial imaging evaluation. Improvements in percutaneous therapy have led to less-invasive and less-costly treatments for nephrolithiasis. This article describes some of these new approaches to diagnosing and caring for patients with renal stone disease.