GC/MS detection of paraffins in a case of lipoid pneumonia following occupational exposure to oil spray

J Anal Toxicol. 1990 Nov-Dec;14(6):372-4. doi: 10.1093/jat/14.6.372.

Abstract

A case of lipoid pneumonia following occupational exposure to oil spray is described. Biological fluids (broncho-alveolar lavage and pleural fluid) are analyzed to determine if the compounds found in the industrial oils are present. The samples are purified using high-performance thin-layer chromatography, and after extraction, the compounds were submitted to infrared spectroscopy. Direct hexane extraction of biological fluids is also performed, followed by gas chromatography/mass spectrometry (GC/MS).

Publication types

  • Case Reports

MeSH terms

  • Aerosols / adverse effects*
  • Biopsy
  • Bronchoalveolar Lavage Fluid / pathology
  • Chromatography, Thin Layer / methods
  • Gas Chromatography-Mass Spectrometry / methods
  • Humans
  • Lung / pathology
  • Male
  • Middle Aged
  • Occupational Exposure
  • Oils / toxicity*
  • Paraffin / analysis*
  • Pneumonia, Lipid / chemically induced*
  • Spectrophotometry, Infrared / methods

Substances

  • Aerosols
  • Oils
  • Paraffin