Typical cardiac magnetic resonance imaging findings of cardiac amyloidosis

Hellenic J Cardiol. 2010 Sep-Oct;51(5):463-6.

Abstract

We report the case of a 62-year-old man who presented with shortness of breath, lower extremity edema and clinical signs of congestive heart failure. Transthoracic echocardiography demonstrated concentric left ventricular hypertrophy with severe diastolic dysfunction and biatrial enlargement. After aggressive diuresis and clinical improvement, a cardiac magnetic resonance imaging (CMR) examination was performed. The study confirmed the presence of concentric left ventricular hypertrophy with borderline systolic function and impaired diastolic function. Delayed contrast-enhanced imaging indicated diffuse enhancement and lack of adequate signal suppression of the left ventricular myocardium, suggesting the diagnosis of infiltrative heart disease. Rectal biopsy confirmed the diagnosis of amyloidosis. This report presents the typical noninvasive imaging findings of cardiac amyloidosis.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / complications
  • Amyloidosis / diagnosis*
  • Amyloidosis / physiopathology
  • Heart Diseases / complications
  • Heart Diseases / diagnosis*
  • Heart Diseases / physiopathology
  • Humans
  • Hypertrophy, Left Ventricular / complications
  • Hypertrophy, Left Ventricular / diagnostic imaging
  • Hypertrophy, Left Ventricular / physiopathology
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Multiple Myeloma / complications
  • Ultrasonography