ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism

Deborah Lo Giacco; Elisabet Ars; Lluis Bassas; José Jorge Galan; Osvaldo Rajmil; Patricia Ruíz; Jorge Caffaratti; Elena Guarducci; Eduard Ruiz-Castané; Csilla Krausz

doi:10.1016/j.fertnstert.2010.08.051

ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism

Fertil Steril. 2011 Jan;95(1):369-71, 371.e1-2. doi: 10.1016/j.fertnstert.2010.08.051.

Authors

Deborah Lo Giacco¹, Elisabet Ars, Lluis Bassas, José Jorge Galan, Osvaldo Rajmil, Patricia Ruíz, Jorge Caffaratti, Elena Guarducci, Eduard Ruiz-Castané, Csilla Krausz

Affiliation

¹ Andrology Service, Molecular Biology Laboratory, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain.

PMID: 20887985
DOI: 10.1016/j.fertnstert.2010.08.051

Abstract

The ESR1 promoter microsatellite (TA)n was reported as a potential functional polymorphism. In a case-control study, we were unable to demonstrate any association between (TA)n and nonsyndromic cryptorchidism in Italian and Spanish study populations.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Child
Cryptorchidism / genetics*
Estrogen Receptor alpha / genetics*
Gene Frequency
Genotype
Humans
Italy
Male
Polymorphism, Genetic / genetics*
Promoter Regions, Genetic / genetics*
Spain

Substances

ESR1 protein, human
Estrogen Receptor alpha