In the experiments performed on 100 white non-inbred male rats (some of them have been kept at the altitude of 3.488 m in the station Vostok, and others--at the coastal level in the station Mirny) testes have been studied, as well as morphometric analysis of convoluted seminiferous tubules and estimation of spermatogenesis activity. During the first month of living at the altitude the section area of the convoluted seminiferous tubules decreases, while the area of their lumen increases. During subsequent periods in the animals, living at the altitude, differences in the parameters, in comparison with the control, disappear. During the first 6 months of their living at the altitude a sharp decrease in spermatogenesis activity is observed. A month of life at the coastal level (after 10 months of hypoxic effect) does not result in normalization of the spermatogenesis activity.