Objective: To evaluate whether taking into account anti-deamidated gliadin peptide (DGP) antibody concentrations improves clinical interpretation.
Design and methods: We calculated likelihood ratios (LR) using data from two previously published studies for assays from EUROIMMUN and INOVA.
Results: LRs markedly increased with increasing IgG anti-DGP concentrations. LRs also increased with increasing IgA anti-DGP concentrations, although they were lower than for IgG anti-DGP.
Conclusions: Use of LRs for different test result intervals improves clinical interpretation.
Copyright © 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.