A novel primary KIT exon 9 single nucleotide substitution c.1427G>T (p.Ser476Ile) in a gastrointestinal stromal tumor

Virchows Arch. 2010 Nov;457(5):623-5. doi: 10.1007/s00428-010-0987-4. Epub 2010 Oct 5.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use
  • Base Sequence
  • Benzamides
  • Combined Modality Therapy
  • Digestive System Surgical Procedures
  • Disease Progression
  • Exons
  • Gastrointestinal Stromal Tumors / genetics*
  • Gastrointestinal Stromal Tumors / pathology*
  • Gastrointestinal Stromal Tumors / therapy
  • Humans
  • Imatinib Mesylate
  • Indoles / therapeutic use
  • Liver Neoplasms / secondary
  • Male
  • Molecular Sequence Data
  • Peritoneal Neoplasms / secondary
  • Piperazines / therapeutic use
  • Polymerase Chain Reaction
  • Polymorphism, Single Nucleotide / genetics*
  • Proto-Oncogene Proteins c-kit / genetics*
  • Pyrimidines / therapeutic use
  • Pyrroles / therapeutic use
  • Sunitinib

Substances

  • Antineoplastic Agents
  • Benzamides
  • Indoles
  • Piperazines
  • Pyrimidines
  • Pyrroles
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit
  • Sunitinib