Volume-based and surface-based algorithms for three-dimensional rendering of computed tomography (CT) scans of the human skull were compared in patients with craniofacial anomalies. Both methods were applied to a selected sample of 12 clinical CT studies. The number of sections ranged from 24 to 72 and the section thickness from 1.5 to 6.0 mm. Volume renderings were more prone to interpolation artifacts but captured the anatomy in greater detail. The sites of closed cranial sutures, visualized using the volume technique, were not demonstrated using the specific surface rendering technique used in this study. In both techniques the areas of thin bone appeared as gaps.