Fully automated production of iodine-124 using a vertical beam

Appl Radiat Isot. 2011 Jan;69(1):146-57. doi: 10.1016/j.apradiso.2010.09.010. Epub 2010 Sep 22.

Abstract

A fully automated system for the production of iodine-124, based on techniques of vertical-beam irradiation and dry distillation, was developed. The system, coupled with a capsulated target, was able to irradiate the (124)TeO(2) target up to 29 μA for 1-4h, which yielded iodine-124 with an almost constant yield of 6.9 MBq/μAh at the end of bombardment. All procedures were performed automatically and repeatedly. The newly developed system would be suitable for routine, large-scale productions of iodine-124.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Iodine Radioisotopes / chemistry*
  • Positron-Emission Tomography / methods*

Substances

  • Iodine Radioisotopes