Abstract
We investigated the effect of letrozole, an aromatase inhibitor, on body mass index, serum hormones, and sperm parameters in infertile men with decreased T:E(2) ratios. All sperm parameters increased after letrozole treatment. Letrozole may be effectively used to improve sperm parameters in infertile men with a low serum T:E(2) ratio.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
MeSH terms
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Adult
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Aromatase Inhibitors / pharmacology
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Body Mass Index*
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Estradiol / blood
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Hormones / blood*
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Humans
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Infertility, Male / blood*
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Infertility, Male / pathology*
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Infertility, Male / physiopathology
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Letrozole
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Male
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Middle Aged
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Nitriles / pharmacology*
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Semen Analysis
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Spermatozoa / drug effects*
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Spermatozoa / pathology
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Testosterone / blood
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Triazoles / pharmacology*
Substances
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Aromatase Inhibitors
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Hormones
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Nitriles
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Triazoles
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Testosterone
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Estradiol
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Letrozole