Abstract
The present study describes a new diagnostic approach for carcinogenesis based on the different tissue redox activity of normal and cancer-bearing mammalians and its visualization and estimation by cell permeable and DNA annealing probe (nitroxide-labeled nitrosourea) and magnetic resonance imaging.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Brain / pathology
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Contrast Media
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Electron Spin Resonance Spectroscopy
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Magnetic Resonance Imaging / methods*
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Mice
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Neoplasms / diagnosis*
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Neoplasms / metabolism*
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Nitrogen Oxides / metabolism
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Oxidation-Reduction
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Time Factors
Substances
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Contrast Media
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Nitrogen Oxides
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nitroxyl