Simple bone cyst (SBC) is an intraosseous pseudocyst that appears as a radiolucent lesion, frequently observed among young patients. In this article we report six cases of SBC and propose a protocol for minimal surgical intervention in the management of this condition. No history of trauma was reported. All patients underwent a minimal bone intervention procedure to perforate the cortical bone and stimulate blood clot formation. Complete healing and no recurrence were observed after 1-year follow-up. This treatment shows advantages such as the establishment of a definitive diagnosis and low invasiveness, particularly in pediatric patients.
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