Intraoperative spectral domain optical coherence tomography for vitreoretinal surgery

Opt Lett. 2010 Oct 15;35(20):3315-7. doi: 10.1364/OL.35.003315.

Abstract

We demonstrate in vivo human retinal imaging using an intraoperative microscope-mounted optical coherence tomography system (MMOCT). Our optomechanical design adapts an Oculus Binocular Indirect Ophthalmo Microscope (BIOM3), suspended from a Leica ophthalmic surgical microscope, with spectral domain optical coherence tomography (SD-OCT) scanning and relay optics. The MMOCT enables wide-field noncontact real-time cross-sectional imaging of retinal structure, allowing for SD-OCT augmented intrasurgical microscopy for intraocular visualization. We experimentally quantify the axial and lateral resolution of the MMOCT and demonstrate fundus imaging at a 20Hz frame rate.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Humans
  • Imaging, Three-Dimensional
  • Retina / anatomy & histology*
  • Retinoscopes
  • Swine
  • Tomography, Optical Coherence / instrumentation
  • Tomography, Optical Coherence / methods*
  • Vitreoretinal Surgery / instrumentation*