Cycloheximide-mediated superinduction of genes involves both native and foreign transcripts in rice (Oryza sativa L.)

Plant Physiol Biochem. 2011 Jan;49(1):9-12. doi: 10.1016/j.plaphy.2010.09.010. Epub 2010 Oct 1.

Abstract

Rice seedlings subjected to heat shock show rapid and transient induction of Oshsp17.4-CI, Oshsp17.9A-CI and OsClpB-cyt/hsp100 transcripts. When the seedlings were pre-treated with protein synthesis inhibitor cycloheximide, levels of the above transcripts during heat shock were more elevated than those seen with heat shock alone. Heat stress and cycloheximide co-treatment resulted in higher transcript accumulation in comparison to cycloheximide pre-treatment followed by heat stress. In transgenic plants raised with OsClpB-cyt/hsp100 promoter driving expression of the reporter gus gene, expression of the gus transcript was subjected to similar superinduction event as was seen with native OsClpB-cyt/hsp100 transcripts in untransformed plants. Yeast cells transformed with variably-sized rice ClpB-cyt/hsp100 promoter driving expression of the lacZ reporter transcript showed that specific sequences of the promoter region may be implicated in superinduction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological / drug effects
  • Adaptation, Physiological / genetics*
  • Base Sequence
  • Cycloheximide / pharmacology*
  • Gene Expression / drug effects*
  • Gene Expression Regulation, Plant / drug effects*
  • Genes, Plant*
  • Genes, Reporter
  • Heat-Shock Proteins / genetics*
  • Heat-Shock Proteins / metabolism
  • Lac Operon
  • Oryza / drug effects
  • Oryza / genetics*
  • Oryza / metabolism
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • Plants, Genetically Modified
  • Promoter Regions, Genetic
  • Protein Synthesis Inhibitors / pharmacology
  • Seedlings
  • Stress, Physiological / genetics
  • Transformation, Genetic
  • Yeasts / genetics
  • Yeasts / metabolism

Substances

  • Heat-Shock Proteins
  • Plant Proteins
  • Protein Synthesis Inhibitors
  • Cycloheximide