Perinatal interventions and survival in resource-poor settings: which work, which don't, which have the jury out?

Arch Dis Child. 2010 Dec;95(12):1039-46. doi: 10.1136/adc.2009.179366. Epub 2010 Oct 26.

Abstract

Perinatal conditions make the largest contribution to the burden of disease in low-income countries. Although postneonatal mortality rates have declined, stillbirth and early neonatal mortality rates remain high in many countries in Africa and Asia, and there is a concentration of mortality around the time of birth. Our article begins by considering differences in the interpretation of 'intervention' to improve perinatal survival. We identify three types of

Intervention: a single action, a collection of actions delivered in a package and a broader social or system approach. We use this classification to summarise the findings of recent systematic reviews and meta-analyses. After describing the growing evidence base for the effectiveness of community-based perinatal care, we discuss current concerns about integration: of women's and children's health programmes, of community-based and institutional care, and of formal and informal sector human resources. We end with some thoughts on the complexity of choices confronting women and their families in low-income countries, particularly in view of the growth in non-government and private sector healthcare.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Community Health Services / methods
  • Delivery of Health Care / methods
  • Developing Countries*
  • Evidence-Based Medicine / methods
  • Global Health
  • Humans
  • Infant, Newborn
  • Medically Underserved Area*
  • Perinatal Care / methods*
  • Perinatal Mortality*
  • Public Sector