Therapeutic hotline: Successful treatment of Morbihan's disease with oral prednisolone and doxycycline

Dermatol Ther. 2010 Nov-Dec;23(6):682-5. doi: 10.1111/j.1529-8019.2010.01373.x.

Abstract

Persistent facial swelling can occur as a rare complication of rosacea. This finding is referred to as lymphedematous rosacea or Morbihan's disease. We report a case of a 45-year-old male with no previous history of rosacea who developed bilateral periorbital swelling associated with facial erythema and edema that responded to a combination of oral corticosteroids and doxycycline. Biopsy revealed changes of granulomatous rosacea.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Anti-Bacterial Agents / administration & dosage*
  • Biopsy
  • Doxycycline / administration & dosage*
  • Drug Therapy, Combination
  • Edema / drug therapy*
  • Edema / etiology
  • Edema / pathology
  • Glucocorticoids / administration & dosage*
  • Humans
  • Male
  • Middle Aged
  • Prednisolone / administration & dosage*
  • Rosacea / complications
  • Rosacea / drug therapy*
  • Rosacea / pathology
  • Skin / drug effects*
  • Skin / pathology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Glucocorticoids
  • Prednisolone
  • Doxycycline