Polylactic acid (PLA): research, development and industrialization

Biotechnol J. 2010 Nov;5(11):1125-36. doi: 10.1002/biot.201000135.

Abstract

Polylactide (PLA) is a biodegradable, aliphatic polyester derived from lactic acid. It has similar mechanical properties to polyethylene terephthalate, but has a significantly lower maximum continuous use temperature. PLA products can be recycled after use either by remelting and processing the material a second time or by hydrolyzing to lactic acid, the basic chemical. In this review, the technologies for polymerization of the lactic acid and the comparison of physical, thermal and mechanical properties, biodegradability, and biocompatibility of the PLA and copolymers with other similar polymers are described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Biocompatible Materials / metabolism
  • Lactic Acid / chemistry*
  • Lactic Acid / metabolism
  • Polyesters / chemistry
  • Polyesters / metabolism
  • Polymers / chemistry*
  • Polymers / metabolism

Substances

  • Biocompatible Materials
  • Polyesters
  • Polymers
  • Lactic Acid
  • poly(lactide)