Vulvar puritus for one year

Dermatol Online J. 2010 Oct 15;16(10):10.

Abstract

A 60-year-old menopausal female presented with vulvar itching for one year. She had noticed a whitish lesion on the vulva that slowly increased in size over the year. She had been unsuccessfully treated with oral fluconazole and topical clotrimazole-mometasone combinations and the plaque had gradually spread to involve the clitoris and peri-urethral area. She was neither diabetic nor hypertensive and had no other systemic complaints. Examination revealed a well-defined non-tender whitish plaque situated on her left labia minora and clitoris (Figure 1). A swab from the plaque did not grow any organism. Routine blood chemistry including a VDRL and HIV ELIZA were within normal limits. A punch biopsy from the lesion was taken and histopathology findings were as seen in (Figures 2 and 3).

Publication types

  • Case Reports

MeSH terms

  • Aminoquinolines / administration & dosage
  • Aminoquinolines / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Diagnosis, Differential
  • Female
  • Humans
  • Imiquimod
  • Middle Aged
  • Paget Disease, Extramammary / diagnosis
  • Paget Disease, Extramammary / drug therapy
  • Paget Disease, Extramammary / pathology*
  • Pruritus Vulvae / etiology*
  • Pruritus Vulvae / pathology*
  • Vaginal Creams, Foams, and Jellies
  • Vulvar Neoplasms / diagnosis
  • Vulvar Neoplasms / drug therapy
  • Vulvar Neoplasms / pathology*

Substances

  • Aminoquinolines
  • Antineoplastic Agents
  • Vaginal Creams, Foams, and Jellies
  • Imiquimod