Extended surgery and pelvic exenteration for locally advanced rectal cancer. What are the limits?

Acta Chir Iugosl. 2010;57(3):23-7. doi: 10.2298/aci1003023s.

Abstract

Historically, locally advanced rectal cancers with invasion of tumor into adjacent organs (T4 N1, 2 tumors) have been considered poor prognosis cancers treated with palliative intent. However with the advent of multi-modality therapy and improvement in surgical reconstructive techniques, extended resections for rectal tumors are possible with acceptable patient morbidity and excellent oncological outcomes.

MeSH terms

  • Combined Modality Therapy
  • Humans
  • Neoplasm Recurrence, Local
  • Pelvic Exenteration*
  • Rectal Neoplasms / mortality
  • Rectal Neoplasms / pathology
  • Rectal Neoplasms / surgery*
  • Survival Rate
  • Treatment Outcome