Abstract
Colonization rates of Streptococcus pneumoniae and Staphylococcus aureus are inversely correlated in infants. Several studies have searched for determinants of this negative association. We studied the association between antipneumococcal antibodies with Staphylococcus aureus colonization and the association between antistaphylococcal antibodies with pneumococcal colonization in healthy children in the pneumococcal vaccine era. In the first year of life, no association between maternal IgG levels and colonization was seen. In addition, no association between the IgG and IgA levels in the child versus colonization status was seen.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Bacterial / blood*
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Carrier State / epidemiology*
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Carrier State / microbiology
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Cohort Studies
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Humans
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Infant
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Longitudinal Studies
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Nasopharynx / microbiology
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Netherlands / epidemiology
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / immunology
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Pneumococcal Infections / microbiology
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Prevalence
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / immunology
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / immunology
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Staphylococcus aureus / isolation & purification*
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Streptococcus pneumoniae / immunology
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Streptococcus pneumoniae / isolation & purification*