Abstract
A high-throughput multiplex bead suspension array was developed for the rapid subgenogrouping of EV71 strains, based on single nucleotide polymorphisms observed within the VP1 region with a high sensitivity as low as 1 PFU. Of 33 viral isolates and 55 clinical samples, all EV71 strains were successfully detected and correctly subgenogrouped.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Enterovirus A, Human / genetics*
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Enterovirus A, Human / isolation & purification*
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Enterovirus Infections / diagnosis*
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Enterovirus Infections / virology
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Humans
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Microspheres
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Molecular Sequence Data
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Oligonucleotides / genetics
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RNA, Viral / genetics
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Sequence Analysis, DNA
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Virology / methods*
Substances
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Oligonucleotides
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RNA, Viral
Associated data
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GENBANK/HQ285091
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GENBANK/HQ285092
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GENBANK/HQ285093
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GENBANK/HQ285094
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GENBANK/HQ285095
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GENBANK/HQ285096
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GENBANK/HQ285097
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GENBANK/HQ285098
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GENBANK/HQ285099
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GENBANK/HQ285100
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GENBANK/HQ285101
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GENBANK/HQ285102
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GENBANK/HQ285103
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GENBANK/HQ285104
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GENBANK/HQ285105
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GENBANK/HQ285106
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GENBANK/HQ285107
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GENBANK/HQ285108
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GENBANK/HQ285109