Abstract
Four phenolics, salviaplebeiaside (1), γ-tocopherol (2), chrysosplenol-D (4), and isovitexin (5), along with α-tocoquinone (3) and β-sitosterol (6) were isolated from the aerial parts of Vitex negundo var. cannabifolia. The isolation was performed using bio-assay tracking experiments. The structures of compounds 1-5 were established by spectroscopic means. The antibacterial activities of the compounds were assessed against Escherichia coli, Bacillus subtilis, Micrococcus tetragenus and Pseudomonas fluorescens. Chrysosplenol-D (4) exhibited activities against all the four spoilage microorganisms.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / chemistry*
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Anti-Bacterial Agents / pharmacology*
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Apigenin / chemistry
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Apigenin / pharmacology
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Bacillus subtilis / drug effects
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Escherichia coli / drug effects
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Flavonoids / chemistry
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Flavonoids / pharmacology
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Micrococcus / drug effects
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Phenols / chemistry*
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Phenols / pharmacology*
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Plant Components, Aerial / chemistry*
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Plant Extracts / chemistry*
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Plant Extracts / pharmacology*
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Pseudomonas fluorescens / drug effects
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Sitosterols / chemistry
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Sitosterols / pharmacology
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Vitamin E / analogs & derivatives
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Vitamin E / chemistry
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Vitamin E / pharmacology
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Vitex / chemistry*
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gamma-Tocopherol / chemistry
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gamma-Tocopherol / pharmacology
Substances
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Anti-Bacterial Agents
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Flavonoids
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Phenols
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Plant Extracts
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Sitosterols
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Vitamin E
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gamma-sitosterol
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tocopherylquinone
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Apigenin
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gamma-Tocopherol
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isovitexin