Implant surface characteristics influence the outcome of treatment of peri-implantitis: an experimental study in dogs

J Clin Periodontol. 2011 Jan;38(1):58-64. doi: 10.1111/j.1600-051X.2010.01631.x. Epub 2010 Nov 24.

Abstract

Aim: To analyse the effect of surgical treatment of peri-implantitis without systemic antibiotics at different types of implants.

Material and methods: Four implants representing four different implant systems - turned (Biomet 3i), TiOblast (Astra Tech AB), SLA (Straumann AG) and TiUnite (Nobel Biocare AB) were placed in the left side of the mandible in six dogs, 3 months after tooth extraction. Experimental peri-implantitis was initiated by placement of ligatures and plaque formation. The ligatures were removed when about 40-50% of the supporting bone was lost. Four weeks later, surgical therapy including mechanical cleaning of implant surfaces was performed. No systemic antibiotics or local chemical antimicrobial therapy were used. After 5 months, block biopsies were obtained and prepared for histological analysis.

Results: Two of the TiUnite implants were lost after surgical therapy. Radiographic bone gain occurred at implants with turned, TiOblast and SLA surfaces, while at TiUnite implants additional bone loss was found after treatment. Resolution of peri-implantitis was achieved in tissues surrounding implants with turned and TiOblast surfaces.

Conclusion: Resolution of peri-implantitis following treatment without systemic or local antimicrobial therapy is possible but the outcome of treatment is influenced by implant surface characteristics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alveolar Bone Loss / diagnostic imaging
  • Alveolar Bone Loss / etiology
  • Alveolar Bone Loss / pathology
  • Alveolar Bone Loss / surgery*
  • Animals
  • Dental Implants / adverse effects*
  • Dental Prosthesis Design / adverse effects*
  • Dogs
  • Ligation
  • Peri-Implantitis / etiology
  • Peri-Implantitis / pathology
  • Peri-Implantitis / surgery*
  • Prosthesis-Related Infections / diagnostic imaging
  • Prosthesis-Related Infections / etiology
  • Prosthesis-Related Infections / pathology
  • Prosthesis-Related Infections / surgery
  • Radiography
  • Random Allocation
  • Surface Properties

Substances

  • Dental Implants