A graphene oxide-based nano-beacon for DNA phosphorylation analysis

Chem Commun (Camb). 2011 Jan 28;47(4):1201-3. doi: 10.1039/c0cc04312e. Epub 2010 Nov 25.

Abstract

We designed a single-fluorophore-tagged hairpin-structured nano-beacon probe by using a superquencher, graphene oxide (GO), based on which a new method for the analysis of DNA phosphorylation detection was developed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / analysis*
  • Fluorescent Dyes / chemistry
  • Graphite / chemistry*
  • Oligonucleotide Probes / chemistry
  • Oxides / chemistry*
  • Phosphorylation
  • Polynucleotide 5'-Hydroxyl-Kinase / metabolism

Substances

  • Fluorescent Dyes
  • Oligonucleotide Probes
  • Oxides
  • Graphite
  • DNA
  • Polynucleotide 5'-Hydroxyl-Kinase