Abstract
The intestine is the home to a vast diversity of microbiota and a complex of mucosal immune system. Multiple regulatory mechanisms control host immune responses to microbiota and maintain intestinal immune homeostasis. This mini review will provide evidence indicating a Treg cell-IgA axis and such axis playing a major role in maintenance of intestinal homeostasis.
Copyright © 2010 Elsevier B.V. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Antigens, Bacterial / immunology
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Homeostasis
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Host-Pathogen Interactions
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Humans
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Immunity, Mucosal
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Immunoglobulin A / immunology*
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Intestines / immunology*
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Intestines / microbiology*
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Metagenome
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T-Lymphocytes, Regulatory / immunology*
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T-Lymphocytes, Regulatory / microbiology
Substances
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Antigens, Bacterial
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Immunoglobulin A