Hospital initiation of a vaccinal schedule improves the long-term vaccinal coverage of ex-preterm children

Vaccine. 2011 Jan 10;29(3):382-6. doi: 10.1016/j.vaccine.2010.11.006. Epub 2010 Nov 25.

Abstract

Preterm infants are experiencing delays in receiving routine schedule vaccines. We evaluated up-to-date immunisation status of 602 preterm infants at 5 and 24 months for DTCoqPolioHib and pneumococcal conjugate vaccine (defined by 3 and 4 doses, respectively). At 5 months, 39% (CI 95% [35-43]) of children were up-to-date for DTCoqPolioHib and 22% (CI 95% [19-26]) for pneumococcal conjugate, while at 24 months 67% (CI 95% [64-71]) were up-to-date for DTCoqPolioHib and 36% (CI 95% [32-40]) for pneumococcal conjugate. After adjustment for gestational age, a primary vaccine before discharge remained linked with a better vaccinal coverage (p<.005, OR=5.0; CI 95% [2.9-8.5]).

MeSH terms

  • Assessment of Medication Adherence*
  • Child, Preschool
  • Diphtheria-Tetanus-Pertussis Vaccine / administration & dosage*
  • Haemophilus Vaccines / administration & dosage*
  • Hospitals*
  • Humans
  • Immunization Schedule*
  • Infant
  • Infant, Newborn
  • Pneumococcal Vaccines / administration & dosage*
  • Poliovirus Vaccine, Inactivated / administration & dosage*
  • Premature Birth
  • Vaccination / methods*
  • Vaccines, Combined / administration & dosage

Substances

  • DTP-IPV-Hib vaccine
  • Diphtheria-Tetanus-Pertussis Vaccine
  • Haemophilus Vaccines
  • Pneumococcal Vaccines
  • Poliovirus Vaccine, Inactivated
  • Vaccines, Combined