[Scan acquisition parameter optimization for the treatment of moving tumors in radiotherapy]

Cancer Radiother. 2011 Apr;15(2):115-22. doi: 10.1016/j.canrad.2010.07.635. Epub 2010 Nov 26.
[Article in French]

Abstract

Aim of the study: In the case of lung tumor treatment, to adjust 3D helical computed tomography (CT) acquisition parameters using a dynamic phantom and compare to the theory the volumes of a moving object.

Materials and methods: Three helical CT acquisitions were compared using a Big Bore CT scan : an "initial" 3D CT scan (constructor parameters), an "optimized" 3D CT scan which parameters are chosen to obtain an axial slow scan like acquisition and a 4D CT scan. We used a phantom composed by a ball filled with water set on a dynamic platform moving in the antero-posterior or cranio-caudal direction with a 14 mm amplitude and a 4s period. For each acquisition and modality (static and dynamic), we quantified the ball volume by automatic contouring and we estimated relative errors.

Results: For an antero-posterior displacement, the volume of the moving ball is under estimated by 14.1 % with the "initial" scan, by 0.2 % with the "optimized" scan and over estimated by 0.8 % with the averaged 4D scan. For a cranio-caudal displacement, it is under estimated by about 22 % with the "initial" scan and by about 1 % with the "optimized" scan and the averaged 4D scan.

Conclusion: Volume measurements performed with the dynamic phantom allowed us to validate the "optimized" 3D CT scan parameters because it accurately reflects the volume of a moving object. Radiotherapy departments without 4D CT should adapt scan parameters for internal target volume definition.

Publication types

  • Validation Study

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / diagnostic imaging*
  • Carcinoma, Non-Small-Cell Lung / radiotherapy*
  • Four-Dimensional Computed Tomography / methods
  • Humans
  • Imaging, Three-Dimensional / methods
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / radiotherapy*
  • Movement*
  • Phantoms, Imaging*
  • Radiotherapy Planning, Computer-Assisted / methods
  • Tomography, Spiral Computed / methods