Background: A 30-year-old immunocompetent male with an unremarkable medical history presented with 2 months of lower abdominal bloating and loose, bloody, mucoid bowel movements. He was clinically suspected to have IBD. Due to the progression of his symptoms, he ultimately required hospitalization for further investigation and care.
Investigations: Full medical history and physical examination, routine blood analyses, stool studies, hepatitis serologic tests, abdominal CT, colonoscopy, PCR analysis and light microscopy and immunoperoxidase staining of colonic biopsy samples.
Diagnosis: Epstein-Barr virus (EBV)-associated lymphoproliferative disorder with diffuse colonic involvement (EBV colitis) in an immunocompetent adult.
Management: Inpatient supportive care.