Abstract
Two new boldine derivatives: the 3-thiocarbamateboldine (3) and the 2,9-O,O-diacetyl-3-thiocarbamateboldine (4) have been synthesized and their cytotoxicity evaluated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemical synthesis*
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Aporphines / chemical synthesis*
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Aporphines / chemistry*
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Aporphines / isolation & purification
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Cell Line, Tumor
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Drug Evaluation, Preclinical
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Humans
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Peumus / chemistry*
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Thiocarbamates / chemical synthesis*
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Thiocarbamates / chemistry*
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Thiocarbamates / isolation & purification
Substances
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2,9-O,O-diacetyl-3-thiocarbamateboldine
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3-thiocarbamateboldine
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Antineoplastic Agents, Phytogenic
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Aporphines
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Thiocarbamates
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boldine