Serum IgG and IgM anticardiolipin antibodies in neurological diseases

Acta Neurol Scand. 1990 Mar;81(3):243-5. doi: 10.1111/j.1600-0404.1990.tb00975.x.

Abstract

To determine whether anti-cardiolipin antibodies (ACA) are associated with multiple sclerosis (MS) or myasthenia gravis (MG), sera from 42 patients suffering from MS and from 21 patients with myasthenia were studied, using an enzyme-linked immunosorbent assay (ELISA). No significant difference in IgG or IgM immunoglobulin isotypes between the MS myasthenic patients and controls was found.

MeSH terms

  • Adolescent
  • Adult
  • Cardiolipins / immunology*
  • Female
  • Humans
  • Immunoglobulin gamma-Chains / metabolism
  • Immunoglobulin mu-Chains / metabolism
  • Male
  • Middle Aged
  • Multiple Sclerosis / immunology*
  • Myasthenia Gravis / immunology*

Substances

  • Cardiolipins
  • Immunoglobulin gamma-Chains
  • Immunoglobulin mu-Chains