Lichtheimia corymbifera subcutaneous infection successfully treated with amphotericin B, early debridement, and vacuum-assisted closure

J Pediatr Surg. 2010 Dec;45(12):e13-5. doi: 10.1016/j.jpedsurg.2010.08.011.

Abstract

Lichtheimia corymbifera (syn. Absidia corymbifera, Mycocladus corymbifer) is an ubiquitous cosmopolitan mold that can cause primary cutaneous and deep tissue infection in healthy individuals. We report a subcutaneous L. corymbifera infection in a 13-year-old immune-competent child, with a severe traumatic injury, with a successful outcome after early diagnosis and treatment with lipid amphotericin B, early debridement, and vacuum-assisted closure (VAC).

Publication types

  • Case Reports

MeSH terms

  • Absidia / isolation & purification*
  • Accidents, Traffic
  • Adolescent
  • Amphotericin B / therapeutic use*
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Bacteremia / drug therapy
  • Bacteremia / etiology
  • Combined Modality Therapy
  • Compartment Syndromes / etiology
  • Compartment Syndromes / surgery*
  • Debridement*
  • Early Diagnosis
  • Fractures, Bone / complications
  • Humans
  • Immunocompetence
  • Leg Bones / injuries
  • Male
  • Mucormycosis / diagnosis
  • Mucormycosis / drug therapy
  • Mucormycosis / microbiology*
  • Mucormycosis / surgery
  • Multiple Trauma
  • Negative-Pressure Wound Therapy*
  • Opportunistic Infections / diagnosis
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / microbiology*
  • Opportunistic Infections / surgery
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / drug therapy
  • Surgical Wound Infection / microbiology*
  • Surgical Wound Infection / surgery
  • Wound Infection / complications

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • liposomal amphotericin B
  • Amphotericin B