Very few studies have addressed the repair of autogenous and prosthetic-related false arteriovenous access (AVA) aneurysms in hemodialysis patients. Surgical management of complicated AVA-related aneurysms remains the gold standard method although covered stents have recently been introduced for the exclusion of such aneurysms, offering a minimally invasive therapy. In this paper, we describe a combination of open and endovascular repair for treating an anastomotic and a puncture-site aneurysm to salvage a failing long-standing autogenous radial-cephalic fistula in the wrist. Resection of the anastomotic aneurysm and reconstruction of the anastomosis proximally was initially performed. Via the first cm of the anastomosis, a Fluency® stent graft (SG) was inserted and it successfully excluded the mid-outflow vein false aneurysm. Such hybrid therapies may be the future of AVA revisions and this trend should not be overlooked by nephrologists and vascular surgeons.