Novel T-RFLP method to investigate six main groups of 2,4-diacetylphloroglucinol-producing pseudomonads in environmental samples

J Microbiol Methods. 2011 Mar;84(3):379-87. doi: 10.1016/j.mimet.2010.11.012. Epub 2010 Dec 7.

Abstract

Strains of fluorescent pseudomonads producing 2,4-diacetylphloroglucinol (DAPG) are involved in the protection of plant roots against soil-borne plant pathogens. Recently, a multilocus sequence analysis of a world wide collection of DAPG-producers led to the identification of six main groups (A-F). In this study a T-RFLP method based on the phlD gene was developed to efficiently identify the members of these six groups in environmental samples. A combination of six restriction enzymes was identified which leads to group specific terminal fragments (T-RF). The detection limit of the phlD-T-RFLP method was determined for the two P. fluorescens strains F113 (group B) and CHA0 (group F) in rhizosphere samples and was found to be 5×10(3)CFU/g and 5×10(4)CFU/g respectively. PhlD-T-RFLP and phlD-DGGE analysis of wheat and maize root samples from greenhouse and field revealed similarly the presence of multilocus groups A, B and D. However, they were more frequently detected with phlD-T-RFLP. Additionally, groups C and F were detected in greenhouse samples but only by phlD-T-RFLP and not by phlD-DGGE. In conclusion, the new phlD-T-RFLP method proved to be a fast and reliable method to detect strains of the six main groups of DAPG-producers in environmental samples with an improved detection limit compared to phlD-DGGE.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics
  • Bacteriological Techniques / methods*
  • Electrophoresis, Polyacrylamide Gel
  • Environmental Microbiology*
  • Nucleic Acid Denaturation
  • Phloroglucinol / analogs & derivatives
  • Phloroglucinol / metabolism
  • Polymorphism, Restriction Fragment Length*
  • Pseudomonas / classification*
  • Pseudomonas / genetics*
  • Pseudomonas / isolation & purification
  • Rhizosphere*
  • Triticum
  • Zea mays

Substances

  • Bacterial Proteins
  • PhlD protein, Pseudomonas
  • 2,4-diacetylphloroglucinol
  • Phloroglucinol