Synthesis of the (-)-TAN-2483B ring system via a D-mannose-derived cyclopropane

Org Biomol Chem. 2011 Feb 21;9(4):998-1000. doi: 10.1039/c0ob00851f. Epub 2010 Dec 14.

Abstract

The ring system of the fungal metabolite (-)-TAN-2483B has been synthesised, for the first time, from d-mannose, utilising a cyclopropanation/ring expansion sequence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cyclopropanes / chemistry*
  • Lactones / chemical synthesis*
  • Mannose / chemistry*
  • Molecular Structure
  • Pyrans / chemical synthesis*
  • Stereoisomerism

Substances

  • Cyclopropanes
  • Lactones
  • Pyrans
  • TAN-2483B
  • cyclopropane
  • Mannose