Refractory cervical esophagogastric anastomotic strictures: management and outcomes

J Thorac Cardiovasc Surg. 2011 Feb;141(2):444-8. doi: 10.1016/j.jtcvs.2010.10.011. Epub 2010 Dec 15.

Abstract

Objective: For recalcitrant cervical esophagogastric anastomotic strictures after transhiatal esophagectomy, a protocol of self-dilatation was developed at the University of Michigan Medical Center, as previously described. This study was undertaken to determine the outcomes of this treatment.

Methods: Self-dilatation was required in 158 (7.6%) of 2075 patients with cervical esophagogastric anastomotic strictures after transhiatal esophagectomy. An esophageal-specific survey evaluated the frequency and duration of dilatation, swallowing function, and satisfaction with treatment. The relationship among anastomotic leak, subsequent stricture, and the need for self-dilatation was assessed. A validated survey tool, the Short Form 36-item, version 2, was used to assess quality of life.

Results: At the time of this study, 78 of 158 patients were alive; 34 (43%) participated in the esophageal-specific survey. Median duration of self-dilatation was 10 years. The majority were satisfied with their ability to eat. No adverse events were reported. All patients said they would use self-dilatation therapy again under similar circumstances. Of these patients, 20 (59%) responded to the Short Form 36-item, version 2. Compared with the general population, 55% and 70% of participants scored at or above the norm for physical health and mental health status, respectively. Patients who required self-dilatation were twice as likely to have a history of cervical esophagogastric anastomotic leak as those who did not require this therapy (P=.0002).

Conclusions: Refractory cervical esophagogastric anastomotic strictures are best managed initially with frequent outpatient dilatations, then transitioning to self-dilatation. Home use of Maloney dilators is a safe, well-tolerated, convenient, and cost-effective way to maintain comfortable swallowing. The effectiveness of self-dilatation therapy is reflected in this cohort's good quality of life and level of functioning.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anastomosis, Surgical
  • Chi-Square Distribution
  • Deglutition
  • Deglutition Disorders / etiology
  • Deglutition Disorders / physiopathology
  • Deglutition Disorders / therapy*
  • Dilatation
  • Esophageal Stenosis / etiology
  • Esophageal Stenosis / physiopathology
  • Esophageal Stenosis / therapy*
  • Esophagectomy / adverse effects*
  • Esophagogastric Junction / physiopathology
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Michigan
  • Middle Aged
  • Patient Satisfaction
  • Quality of Life
  • Recovery of Function
  • Self Care*
  • Stomach Diseases / etiology
  • Stomach Diseases / physiopathology
  • Stomach Diseases / therapy*
  • Surveys and Questionnaires
  • Time Factors
  • Treatment Outcome