Abstract
In response to peptide pheromones, yeast cells prepare themselves for mating; changes include arrest of the cell cycle and induction of transcription. Proteins involved in this signal transduction pathway include the pheromone receptors, subunits of a G protein, protein kinases and DNA-binding proteins. Understanding of this pathway has been facilitated by yeast genetics, which has allowed the genes encoding all of these proteins to be identified and characterized.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Cell Cycle / physiology
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Chemoreceptor Cells / metabolism
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GTP-Binding Proteins / metabolism
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Genes, Fungal
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Pheromones / genetics
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Pheromones / metabolism*
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Receptors, Cell Surface
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Saccharomyces cerevisiae / genetics
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Saccharomyces cerevisiae / metabolism*
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Signal Transduction / physiology
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Transcription, Genetic
Substances
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Pheromones
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Receptors, Cell Surface
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GTP-Binding Proteins