Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes

Fertil Steril. 2011 Apr;95(5):1845-8. doi: 10.1016/j.fertnstert.2010.11.047. Epub 2010 Dec 17.

Abstract

A prospective study was performed to assess the relationship between human papillomavirus (HPV) infection in 199 infertile couples and outcome of assisted reproductive technologies (ARTs). A highly statistically significant correlation between pregnancy loss rate (proportion of pregnancies detected by β-hCG that did not progress beyond 20 weeks) and positive HPV DNA testing in the male partner of infertile couples, compared with HPV negatives, was observed (66.7% vs. 15%).

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Alphapapillomavirus / physiology
  • Family Characteristics
  • Female
  • Fertilization in Vitro / methods*
  • Fertilization in Vitro / statistics & numerical data
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control
  • Infertility / complications*
  • Infertility / epidemiology
  • Infertility / therapy*
  • Infertility / virology
  • Male
  • Papillomavirus Infections / complications*
  • Papillomavirus Infections / epidemiology
  • Papillomavirus Infections / prevention & control
  • Papillomavirus Infections / transmission
  • Pregnancy
  • Pregnancy Outcome*
  • Treatment Outcome