The 3'-UTR AACCins5874 in the stratum corneum chymotryptic enzyme gene (SCCE/KLK7), associated with atopic dermatitis; causes an increased mRNA expression without altering its stability

J Dermatol Sci. 2011 Feb;61(2):131-3. doi: 10.1016/j.jdermsci.2010.11.013. Epub 2010 Dec 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3' Untranslated Regions / genetics
  • Alleles
  • Animals
  • COS Cells / metabolism
  • Cells, Cultured
  • Chlorocebus aethiops
  • Dermatitis, Atopic / genetics*
  • Gene Expression
  • HeLa Cells / metabolism
  • Humans
  • Kallikreins / genetics*
  • Kallikreins / metabolism*
  • Mutagenesis, Insertional
  • Polymorphism, Single Nucleotide
  • RNA, Messenger / metabolism*

Substances

  • 3' Untranslated Regions
  • RNA, Messenger
  • KLK7 protein, human
  • Kallikreins