microRNA methylation profile has prognosis impact in acute lymphoblastic leukemia patients undergoing stem cell transplantation

Biol Blood Marrow Transplant. 2011 May;17(5):745-8. doi: 10.1016/j.bbmt.2010.11.030. Epub 2010 Dec 21.

Authors

Vanesa Martín-Palanco¹, Guillermo Rodríguez, Carmen Martín, Rafael Rojas, Antonio Torres, José Román-Gómez

Affiliation

¹ Hematology Department, Reina Sofia Hospital, Maimonides Institute for Biomedical Research, Córdoba, Spain.

PMID: 21172447
DOI: 10.1016/j.bbmt.2010.11.030

No abstract available

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Biomarkers, Tumor / analysis*
Biomarkers, Tumor / genetics*
Biomarkers, Tumor / metabolism
Bone Marrow Cells / cytology
Bone Marrow Cells / metabolism
Child
Cyclin-Dependent Kinase 6 / genetics
Cyclin-Dependent Kinase 6 / metabolism*
Disease-Free Survival
Epigenesis, Genetic
Female
Gene Expression
Humans
Male
Methylation
MicroRNAs / analysis*
MicroRNAs / genetics*
MicroRNAs / metabolism
Microchip Analytical Procedures
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma / mortality
Precursor Cell Lymphoblastic Leukemia-Lymphoma / physiopathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
Predictive Value of Tests
Risk Factors
Spain
Stem Cell Transplantation / mortality
Up-Regulation

Substances

Biomarkers, Tumor
MicroRNAs
CDK6 protein, human
Cyclin-Dependent Kinase 6