The cauliflower Orange gene enhances petiole elongation by suppressing expression of eukaryotic release factor 1

New Phytol. 2011 Apr;190(1):89-100. doi: 10.1111/j.1469-8137.2010.03578.x. Epub 2010 Dec 22.

Abstract

The cauliflower (Brassica oleracea var. botrytis) Orange (Or) gene affects plant growth and development in addition to conferring β-carotene accumulation. This study was undertaken to investigate the molecular basis for the effects of the Or gene mutation in on plant growth. The OR protein was found to interact with cauliflower and Arabidopsis eukaryotic release factor 1-2 (eRF1-2), a member of the eRF1 family, by yeast two-hybrid analysis and by bimolecular fluorescence complementation (BiFC) assay. Concomitantly, the Or mutant showed reduced expression of the BoeRF1 family genes. Transgenic cauliflower plants with suppressed expression of BoeRF1-2 and BoeRF1-3 were generated by RNA interference. Like the Or mutant, the BoeRF1 RNAi lines showed increased elongation of the leaf petiole. This long-petiole phenotype was largely caused by enhanced cell elongation, which resulted from increased cell length and elevated expression of genes involved in cell-wall loosening. These findings demonstrate that the cauliflower Or gene controls petiole elongation by suppressing the expression of eRF1 genes, and provide new insights into the molecular mechanism of leaf petiole regulation.

Keywords: Or gene; cauliflower (Brassica oleracea); cell length; eRF1-2; petiole elongation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Brassica / genetics*
  • Cell Nucleus / metabolism
  • Gene Expression Regulation, Plant
  • Genes, Plant*
  • Molecular Sequence Data
  • Mutation / genetics
  • Peptide Termination Factors / metabolism*
  • Plant Epidermis / cytology
  • Plant Leaves / genetics*
  • Plant Leaves / growth & development*
  • Plant Proteins / genetics
  • Plant Proteins / metabolism*
  • Protein Binding
  • RNA Interference
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Sequence Alignment
  • Sequence Analysis, Protein
  • Subcellular Fractions / metabolism

Substances

  • Peptide Termination Factors
  • Plant Proteins
  • RNA, Messenger